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Michael Stockton, BS

Graduate student, Neuroscience

Michael received his B.S. from UW-Madison, where he worked in the lab of Dr. Xinyu Zhao studying the molecular mechanisms of neurogenesis. In 2019 he moved to Colorado to join the Neuroscience PhD program. Michael uses in vivo imaging to investigate the process of new oligodendrocyte integration in the cortex. Outside of lab, Michael enjoys neuroscience outreach, hiking, and hanging out with his partner and two cats.

Research Projects

Premyelinating Oligodendrocyte (PreOL) survival and integration: I use 2-Photon imaging of transgenic mice to investigate the process of premyelinating oligodendrocyte survival and integration in the mouse cortex.

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Microglia - Oligodendrocyte Interactions in the central nervous system: I use 2-Photon imaging to observe interactions between microglia and oligodendrocytes in the intact central nervous system.

Honors and Awards

  • National Science Foundation Graduate Research Fellowship Program (NSF-GRFP)                                                                             

    • Honorable Mention

  • Neuroscience Program Training Grant                                                                                                                                                    

    • Selected for and awarded funding by the Neuroscience Training Program T32 grant to fund research during the second year of my PhD.

  • Intellectual And Developmental Disabilities Research Center Award (IDDRC) Undergraduate Student         

    • For outstanding achievement in the IDDRC of the Waisman Center, University of Wisconsin-Madison

Publications

  • Hughes, Ethan G., and Michael E. Stockton. 2021. “Premyelinating Oligodendrocytes: Mechanisms Underlying Cell Survival and Integration.” Frontiers in Cell and Developmental Biology 9: 1985. https://doi.org/10.3389/fcell.2021.714169.

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  • Shen, Minjie, Yu Guo, Qiping Dong, Yu Gao, Michael E. Stockton, Meng Li, Sudharsan Kannan, et al. 2021. “FXR1 Regulation of Parvalbumin Interneurons in the Prefrontal Cortex Is Critical for Schizophrenia-like Behaviors.” Molecular Psychiatry, April, 1–23. https://doi.org/10.1038/s41380-021-01096-z.

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  • Minjie Shen, Feifei Wang, Meng Li, Nirnath Sah, Michael Stockton, Joseph Tidei, Yu Gao, Sudharsan Kannan, Henriette van Praag, and Xinyu Zhao. (2019). “Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.” Nature Neuroscience. 22, 386-400.

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  • Jichao Sun, Jared Carlson-Stevermer, Uptal Das, Minjie Shen, Lina Wang, Jon Loi, Andrew Petersen, Michael Stockton, Marion Delenclos, Pamela Mclean, Anita Bhattacharyya, Matthew Jones, Xinyu Zhao, Krishanu Saha, Subhojit Roy. (2019) “CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage.” Nature Communications. 10, 53.  

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  • Y. Li, Michael Stockton, Brian E. Eisinger, Jessica Miller, Yinghua Zhao, Ismat Bhuiyan, Yu Gao, Zhiping Wu, Junmin Peng, Xinyu Zhao. (2018). “Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome.” Nature Communications. Vol. 9, 2494.

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  • Yue Li, Minjie Shen, Michael Stockton. (2018) “Hippocampal deficits in neurodevelopmental disorders” Neurobiology of Learning and Memory.

 

  • Y. Li, Michael Stockton, Ismat Bhuiyan, Brian E. Eisinger, Yu Gao, Jessica L. Miller, Anita Bhattacharyya, and Xinyu Zhao. (2016) “MDM2 inhibition rescues neurogenic and cognitive deficits in fragile X mice.” Science Translational Medicine. Vol. 8, Issue 336.​​​​​

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